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total parp  (Proteintech)


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    Proteintech total parp
    Total Parp, supplied by Proteintech, used in various techniques. Bioz Stars score: 96/100, based on 736 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/total parp/product/Proteintech
    Average 96 stars, based on 736 article reviews
    total parp - by Bioz Stars, 2026-03
    96/100 stars

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    Knockdown <t>of</t> <t>AURKA</t> increases apoptosis induced by cisplatin or radiation. ( A ) Expressions of <t>C-PARP,</t> AURKA, and GADPH were shown in PC9 and A549 cells with and without the treatment of cisplatin and/or doxycycline for 48 h. ( B ) Expressions of C-PARP, AURKA, and GADPH were shown in PC9 and A549 cells (with and without the treatment of radiation and/or doxycycline for 48 h). The ratios of band intensities divided by GAPDH are noted at the top of each protein band.
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    Knockdown of AURKA increases apoptosis induced by cisplatin or radiation. ( A ) Expressions of C-PARP, AURKA, and GADPH were shown in PC9 and A549 cells with and without the treatment of cisplatin and/or doxycycline for 48 h. ( B ) Expressions of C-PARP, AURKA, and GADPH were shown in PC9 and A549 cells (with and without the treatment of radiation and/or doxycycline for 48 h). The ratios of band intensities divided by GAPDH are noted at the top of each protein band.

    Journal: Cancers

    Article Title: Aurora Kinase A Inhibition Potentiates Platinum and Radiation Cytotoxicity in Non-Small-Cell Lung Cancer Cells and Induces Expression of Alternative Immune Checkpoints

    doi: 10.3390/cancers16162805

    Figure Lengend Snippet: Knockdown of AURKA increases apoptosis induced by cisplatin or radiation. ( A ) Expressions of C-PARP, AURKA, and GADPH were shown in PC9 and A549 cells with and without the treatment of cisplatin and/or doxycycline for 48 h. ( B ) Expressions of C-PARP, AURKA, and GADPH were shown in PC9 and A549 cells (with and without the treatment of radiation and/or doxycycline for 48 h). The ratios of band intensities divided by GAPDH are noted at the top of each protein band.

    Article Snippet: For Western blot analysis, antibodies against AURKA (catalog no. 91590), phospho-Aurora A (Thr288) (catalog no. 3079), total PARP (catalog no. 9532), cleaved PARP (Asp214) (catalog no. 5625), and glyceraldehyde-3-phosphate dehydrogenase (GAPDH) (catalog no. 5174) were sourced from Cell Signaling Technology (Boston, MA, USA).

    Techniques: Knockdown

    Inhibiting AURKA by MLN8237 induces apoptosis and senescence. ( A ) Western blotting: the expression of cleaved PARP and GADPH in PC9 and A549 cells with and without treatment of cisplatin and/or MLN8237 for 48 h. ( B ) Representative picture of staining of senescence-associated beta-galactosidase in PC9 and A549 cells with and without treatment of cisplatin and/or MLN8237. ( C ) Quantitative analysis of staining of senescence-associated beta-galactosidase in PC9 and A549 cells with and without treatment of cisplatin and/or MLN8237.

    Journal: Cancers

    Article Title: Aurora Kinase A Inhibition Potentiates Platinum and Radiation Cytotoxicity in Non-Small-Cell Lung Cancer Cells and Induces Expression of Alternative Immune Checkpoints

    doi: 10.3390/cancers16162805

    Figure Lengend Snippet: Inhibiting AURKA by MLN8237 induces apoptosis and senescence. ( A ) Western blotting: the expression of cleaved PARP and GADPH in PC9 and A549 cells with and without treatment of cisplatin and/or MLN8237 for 48 h. ( B ) Representative picture of staining of senescence-associated beta-galactosidase in PC9 and A549 cells with and without treatment of cisplatin and/or MLN8237. ( C ) Quantitative analysis of staining of senescence-associated beta-galactosidase in PC9 and A549 cells with and without treatment of cisplatin and/or MLN8237.

    Article Snippet: For Western blot analysis, antibodies against AURKA (catalog no. 91590), phospho-Aurora A (Thr288) (catalog no. 3079), total PARP (catalog no. 9532), cleaved PARP (Asp214) (catalog no. 5625), and glyceraldehyde-3-phosphate dehydrogenase (GAPDH) (catalog no. 5174) were sourced from Cell Signaling Technology (Boston, MA, USA).

    Techniques: Western Blot, Expressing, Staining